KDIGO classification of AKI (acute kidney injury)

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 KDIGO (Kidney Disease: Improvement Global Initiative) definition of AKI is characterised by any of the following criteria:

  • Increase S. Creatinine ≥ 0.3 mg/dl within 48 hrs, or 

  • Increase S. Creatinine ≥ 1.5 times the baseline within last 7 days, or

  • Urine volume < 0.5 ml/kg/hr for 6 hrs

Severity of the disease is staged according to the following criteria:


Stage 1:

  • S. creatinine 1.5 - 1.9 times the baseline or Increase > 0.3 mg/dl 

  • Urine output < 0.5 ml/kg/hr for 6 - 12 hrs 

Stage 2:

  • S. creatinine 2.0 - 2.9 times the baseline 

  • Urine output < 0.5 ml/kg/hr for > 12 hrs 

Stage 3:

  • S. creatinine 3.0 times the baseline or Increase > 4.0 mg/dl 

  • eGFR < 35 ml/min 

  • Urine output < 0.3 ml/kg/hr for > 24 hrs

  • Initiation of renal replacement therapy 

    KDIGO

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