Cause of acute flaccid paralysis

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Acute flaccid paralysis in a lower motor neuron lesion which occurs over a period of 15 days.

Aetiologies of acute flaccid paralysis are divided according to anatomical site: 

Spinal cord: 

  • Acute transverse myelitis 
  • Ascending myelitis 
Anterior horn cell: 
  • Poliomyelitis 
  • GBS
Nerve:
  • Acute porphyria 
  • Arsenic poisoning 
Neuromuscular junction:
  • Myasthenia gravis 
  • Hypermagnesemia 
  • Snake venom 
  • Organophosphate 
  • Botulism 
Muscle:
  • Hypokalaemia
  • Periodic paralysis 
  • Viral myositis 
  •  Polymyositis

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