Seizure or Convulsion in pregnancy (including peripartum period)

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 Seizure in pregnancy:

Causes:

  • Eclampsia - 98% (seizure due to pregnancy)
  • Epilepsy (seizure aggravated by pregnancy)
  • Febrile convulsion 
  • Cerebrovascular - 
    • Intracranial haemorrhage 
    • Cerebral venous sinus thrombosis 
    • Ischemic stroke 
    • Space occupying lesion 
    • Amniotic fluid embolism 
    • Air embolism 
    • Posterior reversible encephalopathy syndrome 
    • Reversible cerebral vasoconstriction syndrome 
    • Thrombotic thrombocytopenic purpura 
  • Metabolic - 
    • Hyperemesis gravidarum 
    • Hyperglycaemia or Hypoglycaemia 
    • Electrolyte abnormality - 
      • Hyponatraemia, Hypernatraemia 
      • Hypocalcaemia, Hypercalcemia
      • Hypomagnesaemia  
      • Pyridoxine deficiency 
    • Acute hepatitis (due to fatty liver in pregnancy, viral hepatitis) 
    • Uraemia 
    • Intermittent porphyria 
  • Infection - 
    • Cerebral Maleria
    • Meningitis
    • Encephalitis
    • Cerebral abscess 
  • Psychogenic non epileptic seizure 
  • Tetany 
  • Drug withdrawal - 
    • Cocaine 
    • Alcohol 
  • Local anaesthetic systemic toxicity 

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